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Tag Archives: tuberculosis

Scientists discover how tuberculosis puts the brakes on immune engines

Graphical Abstract. Credit: Cell Reports Scientists from Trinity have discovered both how TB puts the brakes on our immune engines and how we can kick-start those engines back into gear—providing hope that improved treatment options could soon be on the horizon. Although ancient, TB is still the world’s deadliest infectious …

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Compound in green tea plant shows potential for fighting tuberculosis

Credit: CC0 Public Domain An antioxidant found in the green tea plant could become key to tackling tuberculosis one day, a team of international scientists led by Nanyang Technological University, Singapore (NTU Singapore) has found. Through laboratory investigations, the team led by NTU Professor Gerhard Grüber discovered how the prominent …

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Improving tuberculosis screening in remote areas

Finding and testing tuberculosis patients in remote areas can be challenging. Credit: Niklaus Labhardt/Swiss TPH Tuberculosis (TB) is the number one infectious disease killer worldwide. Particularly in hard-to-reach populations, diagnosis and treatment of TB remains very challenging. In high-burden areas, one third of patients are never diagnosed. To find, diagnose …

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How an AI solution can design new tuberculosis drug regimens

Credit: CC0 Public Domain With a shortage of new tuberculosis drugs in the pipeline, a software tool from the University of Michigan can predict how current drugs—including unlikely candidates—can be combined in new ways to create more effective treatments. “This could replace our traditional trial-and-error system for drug development that …

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Boosting host immune defenses to treat tuberculosis

A low-cost drug, nitazoxanide, could curb M. tuberculosis by harnessing cells’ RNA sensors. Credit: NIAID via Flickr Current treatment regimens for Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, are long, complex, and hard for people to sustain. Moreover, the bacteria often develop drug resistance, and many people harbor multi-drug-resistant …

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