treatment

New research on the brain's relay processes could guide treatment for certain brain disorders

New research on the brain’s relay processes could guide treatment for certain brain disorders

Vandana Sampathkumar looks at images from mice brains to study the thalamus at the center of the brain. Credit: Nidhi Sharma, University of Chicago New research shows cells gather more data than once believed inside the thalamus, a relay station of sensory and motor abilities in the brain. That could change how medicine treats schizophrenia, …

New research on the brain’s relay processes could guide treatment for certain brain disorders Read More »

Schematic workflow of SARS-CoV-2 infection modelling. Publicly available COVID-19 datasets are collated into two subsets. Data on the point-to-point signalling pathway interactions of the virus with the host cell, and of the host cell in response to infection, are used to build a network model. Data from experiments showing how the overall behaviour of the infected cell changes under perturbations, such as a potential treatment, are used as a testing dataset to validate the model. The readouts of the model are compared to the testing dataset and the model is refined iteratively until it reproduces all the experimentally observed behaviours. We then screen the effects of potential drug treatments, either singly or in combination, on the model, to find the best predicted therapies for early and late stage severe COVID-19.

In-silico prediction of effective drug combinations for the treatment of SARS-CoV-2 infection

Coronavirus disease 2019 (COVID-19) is a complex disease with a wide range of symptoms, ranging from asymptomatic to very severe. Even though a majority of the people infected with this disease show mild symptoms, the Centers for Disease Control and Prevention (CDC) has reported that in the USA alone, 4.9% of COVID-19 patients required hospitalization, …

In-silico prediction of effective drug combinations for the treatment of SARS-CoV-2 infection Read More »

Race and ethnicity may impact prevalence and treatment of heart valve dysfunction

Race and ethnicity may impact prevalence and treatment of heart valve dysfunction

Graphic showing a normal, healthy aortic valve—the junction between the heart’s main pumping chamber (left ventricle) and the main artery (aorta) supplying oxygen-rich blood to your body—next to one stiff and defective from stenosis. A new Johns Hopkins Medicine study suggests how a faulty heart valve is treated may differ by race and ethnicity. Credit: …

Race and ethnicity may impact prevalence and treatment of heart valve dysfunction Read More »

Clinic transforms cancer treatment by combining diagnosis and therapy

Clinic transforms cancer treatment by combining diagnosis and therapy

Credit: Pixabay/CC0 Public Domain Conventional treatments for cancer, such as chemotherapy, external beam radiation and surgery, don’t always work, but hope is on the horizon for some patients with certain cancers. UC Davis Health is leveraging the next generation in nuclear medicine treatments to attack cancers in ways that traditional options cannot by themselves. The …

Clinic transforms cancer treatment by combining diagnosis and therapy Read More »

New treatment pathways for hepatitis C

New treatment pathways for hepatitis C

Hepatitis C viral load testing on GeneXpert by Than Sitt Charity Clinic laboratory technician. Credit: Kyaw Win Hlaing A newly published Burnet Institute study has demonstrated the feasibility and effectiveness of simplified clinical pathways for treatment of hepatitis C (HCV) in Myanmar. Conducted between January 2019 and August 2020, the study provides endorsement for a …

New treatment pathways for hepatitis C Read More »

Nine of ten patients with hypertension do not receive enough treatment

Nine of ten patients with hypertension do not receive enough treatment

Hypertension (high blood pressure) is the leading treatable cause of illness and death worldwide. More than a billion people are hypertensive, defined as having blood pressure (BP) with a systolic level (the higher number) of at least 140 millimeters of mercury (mmHg) or diastolic level (the lower number) of 90 mmHg or higher. More than …

Nine of ten patients with hypertension do not receive enough treatment Read More »

US clinics slower to provide opioid treatment than Canadian clinics

US clinics slower to provide opioid treatment than Canadian clinics

Credit: Unsplash/CC0 Public Domain As opioid overdose deaths rose during the COVID-19 pandemic, people seeking treatment for opioid addiction had to wait nearly twice as long to begin methadone treatment in the United States than in Canada, a new Yale study has shown. In both countries during the pandemic, about one in 10 methadone clinics …

US clinics slower to provide opioid treatment than Canadian clinics Read More »

Freiburg surgeons develop new treatment method to improve survival after cardiac arrest

Freiburg surgeons develop new treatment method to improve survival after cardiac arrest

Around 50,000 people suffer sudden cardiac arrest in Germany every year. When occurring outside a hospital, the chances of survival are only ten percent. Survivors often suffer from severe permanent neurological damage. On July 21st, 2021, researchers from the Faculty of Medicine – University of Freiburg, Germany, published together with German and US colleagues a …

Freiburg surgeons develop new treatment method to improve survival after cardiac arrest Read More »

Guidelines updated for treatment of sexually transmitted infections

Guidelines updated for treatment of sexually transmitted infections

(HealthDay)—Guidelines for the treatment of people with or at risk for sexually transmitted infections (STIs) have been updated, according to a report published in the July 23 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. Kimberly A. Workowski, M.D., from the CDC in Atlanta, and colleagues updated guidelines …

Guidelines updated for treatment of sexually transmitted infections Read More »

Investigational antipsychotic treatment offers sustained benefits for people with dementia-related psychosis

Investigational antipsychotic treatment offers sustained benefits for people with dementia-related psychosis

Evidence of the sustained benefits of an investigational antipsychotic treatment for people with dementia-related psychosis has been published. Up to half of the 45 million people worldwide who are living with Alzheimer’s disease will experience psychotic episodes, a figure that is even higher in some other forms of dementia. Psychosis is linked to a faster …

Investigational antipsychotic treatment offers sustained benefits for people with dementia-related psychosis Read More »