Tag Archives: system

Overactivation of the neuroimmune gene C4 leads to microglia-mediated engulfment of synapses in the medial prefrontal cortex. This image was taken by Rhushikesh A. Phadke using confocal microscopy. Magenta: microglia (Iba1). Cyan: synapses (PSD95). Yellow: microglia lysosomes (CD68). Credit: Rhushikesh A. Phadke Excessive activity of an immune system gene previously …

The simple fruit fly, Drosophila melanogaster, is used in the Davis lab to study the genetics underlying memory. Credit: Scott Wiseman for Scripps Research Storing and retrieving memories is among the most important tasks our intricate brains must perform, yet how that happens at a molecular level remains incompletely understood. …

Myelin sheath. Credit: Wikipedia. A molecular switch has the ability to turn on a substance in animals that repairs neurological damage in disorders such as multiple sclerosis (MS), Mayo Clinic researchers discovered. The early research in animal models could advance an already approved Food and Drug Administration therapy and also …

Credit: Andrey Popov Gastric bypass vastly improves the health of the patients who elect to receive the surgery. Post-bariatric hypoglycemia, however, can be a severe complication experienced by 10 to 30 percent of patients. Researchers at Joslin Diabetes Center and Harvard John A. Paulson School of Engineering and Applied Sciences …

Credit: CC0 Public Domain The peaceful and delicate co-existence of friendly gut bacteria and the immune system relies on highly coordinated information exchange between immune system cells and certain cells lining the intestine. Until now, scientists generally believed these two cell types were also central to the production of antibacterial …

This graphic shows how HIV can get trapped in an endosome, or pocket, on a CD4+T cell (centre cell). Researchers previously thought this was a dead-end for HIV, because the virus wasn’t able to actually replicated. But the new CEMIR research shows that once HIV is in the endosome and …

Credit: CC0 Public Domain Hospital ratings are intended to help patients decide where to get medical care and encourage hospitals to improve the quality of their services. They also can influence how insurance companies negotiate contracts for reimbursing hospitals. But a University of Chicago Medicine analysis of the Centers for …

(HealthDay)—Peripheral nervous system (PNS) disease is a component of systemic lupus erythematosus (SLE) disease activity and has a significant negative impact on health-related quality of life, according to a study published in the January issue of Arthritis & Rheumatology. John G. Hanly, M.D., from the Queen Elizabeth II Health Sciences …

(HealthDay)—A machine learning system can generate clinically valid alerts for medication errors that might be missed with existing clinical decision support (CDS) systems, according to a study published in the January issue of The Joint Commission Journal on Quality and Patient Safety. Ronen Rozenblum, Ph.D., M.P.H., from Harvard Medical School …

Weight gain and diet have long been known to shuffle the population of gut microbes. More recently, studies have also connected weight gain and diet to changes in the intestinal endocannabinoid system (eCB), a complex network of metabolites and receptors that help regulate appetite and metabolism, among other chores. A …