Tag Archives: system

Hyperactive immune system gene causes schizophrenia-like changes in mice

Overactivation of the neuroimmune gene C4 leads to microglia-mediated engulfment of synapses in the medial prefrontal cortex. This image was taken by Rhushikesh A. Phadke using confocal microscopy. Magenta: microglia (Iba1). Cyan: synapses (PSD95). Yellow: microglia lysosomes (CD68). Credit: Rhushikesh A. Phadke Excessive activity of an immune system gene previously …

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Long-term memory performance depends upon gating system, study finds

The simple fruit fly, Drosophila melanogaster, is used in the Davis lab to study the genetics underlying memory. Credit: Scott Wiseman for Scripps Research Storing and retrieving memories is among the most important tasks our intricate brains must perform, yet how that happens at a molecular level remains incompletely understood. …

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A molecular switch for repairing central nervous system disorders

Myelin sheath. Credit: Wikipedia. A molecular switch has the ability to turn on a substance in animals that repairs neurological damage in disorders such as multiple sclerosis (MS), Mayo Clinic researchers discovered. The early research in animal models could advance an already approved Food and Drug Administration therapy and also …

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In fighting gut infections, nervous system is key, team finds

Credit: CC0 Public Domain The peaceful and delicate co-existence of friendly gut bacteria and the immune system relies on highly coordinated information exchange between immune system cells and certain cells lining the intestine. Until now, scientists generally believed these two cell types were also central to the production of antibacterial …

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Ratings system may penalize hospitals serving vulnerable communities

Credit: CC0 Public Domain Hospital ratings are intended to help patients decide where to get medical care and encourage hospitals to improve the quality of their services. They also can influence how insurance companies negotiate contracts for reimbursing hospitals. But a University of Chicago Medicine analysis of the Centers for …

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Peripheral nervous system events not common in lupus

(HealthDay)—Peripheral nervous system (PNS) disease is a component of systemic lupus erythematosus (SLE) disease activity and has a significant negative impact on health-related quality of life, according to a study published in the January issue of Arthritis & Rheumatology. John G. Hanly, M.D., from the Queen Elizabeth II Health Sciences …

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Machine learning system makes more alerts for med errors

(HealthDay)—A machine learning system can generate clinically valid alerts for medication errors that might be missed with existing clinical decision support (CDS) systems, according to a study published in the January issue of The Joint Commission Journal on Quality and Patient Safety. Ronen Rozenblum, Ph.D., M.P.H., from Harvard Medical School …

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