patients

In Brazil, an NGO grows medical cannabis to help patients

In Brazil, an NGO grows medical cannabis to help patients

Brazilian agronomist Diogo Mantovanelli inspects cannabis plants at the Medical Cannabis Research and Patient Support Association (APEPI) production farm in Paty dos Alferes, Rio de Janeiro state, Brazil on September 9, 2021. Surrounded by barbed wire and an electric fence, marijuana plants flourish under the bright sun on a farm in a mountainous area outside …

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WHO recommends antibody treatment for COVID patients at high risk of hospital admission

WHO recommends antibody treatment for COVID patients at high risk of hospital admission

Credit: CC0 Public Domain A treatment combining two antibodies (casirivimab and imdevimab) is recommended for two specific groups of patients with COVID-19 by a WHO Guideline Development Group (GDG) panel of international experts and patients in The BMJ today. The first are patients with non-severe COVID-19 who are at highest risk of hospitalisation and the …

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Study: Characterisation of the blood RNA host response underpinning severity in COVID-19 patients. Image Credit: Peddalanka Ramesh Babu/ Shutterstock

Differences in blood gene expression among patients with varying COVID-19 severity

Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), but the clinical manifestations are highly variable. While some individuals remain asymptomatic, others manifest mild flu-like symptoms and some contract a severe life-threatening disease requiring mechanical ventilation and intensive care. There have been several deaths reported due to COVID-19. Why …

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Study suggests sonic hedgehog protein pathway stimulation could help Parkinson's patients

Study suggests sonic hedgehog protein pathway stimulation could help Parkinson’s patients

A new study from Malave et al. suggests that in the brains of L-Dopa-treated Parkinson’s patients the lack of Shh signaling to cholinergic neurons results in L-Dopa induced dyskinesia. Credit: Santiago Uribe-Cano. Levodopa, or L-dopa, is considered the most effective treatment for Parkinson’s disease today. After a few years of treatment, however, almost all patients …

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Study: Aging-related cell type-specific pathophysiologic immune responses that exacerbate disease severity in aged COVID-19 patients. Image Credit: Ann Kosolapova/ Shutterstock

Scientists identify potential therapeutic targets to alleviate severe COVID-19 in aged patients

Coronavirus disease 2019 (COVID-19) disproportionately affects patients 65 years and older. Age-related impaired host immunity has been implicated for severe outcomes of COVID-19. Researchers have performed a study on large data set to understand better the molecular basis of vulnerability in aged COVID-19 patients. They observed certain age-linked immunoinflammatory factors associated with severe COVID-19 and …

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Study: Seroresponse to SARS-CoV-2 vaccines among maintenance dialysis patients over six months. Image Credit: Mailsonpignata

Maintenance dialysis patients may need additional shots of COVID-19 vaccines

Researchers in the United States have conducted a study showing that the antibody response to vaccination designed to protect against coronavirus disease 2019 (COVID-19) wanes substantially over time among patients receiving maintenance dialysis. The team’s study of more than 1,500 individuals found that antibody titers against the COVID-19 causative agent – severe acute respiratory syndrome …

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Russia allows booster shots 6 months after vaccination

COVID vaccines do protect patients with cancer

Credit: Unsplash/CC0 Public Domain The long-awaited confirmation of the efficacy of COVID-19 vaccination in patients with cancer has arrived, on time to be disseminated to a global audience at the annual congress of the European Society for Medical Oncology, the leading professional society for medical oncology. With a multitude of studies supporting similar conclusions still …

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Early treatment with ACE inhibitors improves cardiac outcomes of patients with Becker muscular dystrophy

Early treatment with ACE inhibitors improves cardiac outcomes of patients with Becker muscular dystrophy

There is no consensus on when to introduce cardioprotective treatment in patients with Becker muscular dystrophy (BMD), and practice varies widely. A new study published in the Journal of Neuromuscular Diseases concludes that starting treatment with an ACE inhibitor as soon as cardiac function drops below the lower limit of the normal range reduces the …

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Sleep apnea patients struggle as common CPAP machine is recalled

Sleep apnea patients struggle as common CPAP machine is recalled

Millions of U.S. sleep apnea patients are scrambling to find ways to protect their nightly slumber, following a voluntary recall from one of the nation’s leading manufacturers of CPAP breathing machines. Philips Respironics agreed to a voluntary recall of continuous positive airway pressure (CPAP) machines in late June, over concerns that noise-dampening foam inside the …

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Antibody-drug conjugate shows impressive activity in patients with non-small cell lung cancer with mutation in HER2 gene

Antibody-drug conjugate shows impressive activity in patients with non-small cell lung cancer with mutation in HER2 gene

Credit: Pixabay/CC0 Public Domain More than half of patients with non-small cell lung cancer (NSCLC) bearing a mutation in the HER2 gene had their tumors stop growing or shrink for an extended time after treatment with a drug that hitches a chemotherapy agent to a highly targeted antibody, an international clinical trial led by investigators …

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