infection

Infection hinders blood vessel repair following traumatic brain or cerebrovascular injuries

Infection hinders blood vessel repair following traumatic brain or cerebrovascular injuries

Seven days after mTBI, the blood vessels (stained in red) in the tissues around the brain are not completely repaired. A marker for intact vessels was used (labeled in green) to distinguish fully functional blood vessels (yellow) from ones that are still damaged (red). Credit: McGavern Lab, NINDS Traumatic brain injury (TBI) and other injuries …

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Antibodies from original strain COVID-19 infection don't bind to variants

Antibodies from original strain COVID-19 infection don’t bind to variants

People infected with the original strain of the virus that causes COVID-19 produced a consistent antibody response. However, those antibodies don’t bind well to new variants, Illinois graduate student Timothy Tan (left) and professor Nicholas Wu found. Credit: L. Brian Stauffer People infected with the original strain of the virus that causes COVID-19 early in …

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Study: Humoral immune responses against seasonal coronaviruses predict efficiency of SARS-CoV-2 spike targeting, FcγR activation, and corresponding COVID-19 disease severity. Image Credit: NIAID

The influence of prior seasonal coronavirus infection on disease severity in COVID-19

Severe acute respiratory syndrome coronavirus (SARS-CoV-2) is a novel virus that causes coronavirus disease (COVID-19). Early detection of Immunoglobulin G (IgG) against SARS-CoV-2 spike proteins in COVID-19 patients has been reported, which is not typically observed in other infections. It has been suggested that the early response may be the result of prior exposure to …

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COVID-19 vaccine booster dose cuts infection in those 60 and older

COVID-19 vaccine booster dose cuts infection in those 60 and older

(HealthDay)—Among Israeli adults aged 60 years and older, those receiving a third booster dose of the Pfizer-BioNTech COVID-19 vaccine have rates of confirmed COVID-19 and severe illness that are substantially lower than the rates seen for individuals only receiving the two original vaccine doses, according to a study published online Sept. 15 in the New …

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Ebola virus in survivors can trigger outbreaks years after infection

Ebola virus in survivors can trigger outbreaks years after infection

Ebola virus particles (red) on a larger cell. Credit: NIAID Ebola survivors can relapse and trigger outbreaks at least five years after infection, and long-term follow-up of former patients is needed to prevent devastating flare-ups, according to new research. Scientists already knew Ebola could lie dormant in survivors, who test negative because the virus is …

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Study: Differential antibody dynamics to SARS-CoV-2 infection and vaccination. Image Credit: Andrii Vodolazhskyi/ Shutterstock

Natural SARS-CoV-2 infection induces more durable immunity than vaccination

In a report currently available on the bioRxiv* preprint server, scientists from the USA have demonstrated that immunity induced by mRNA-based coronavirus disease 2019 (COVID-19) vaccines in previously severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected people has the highest robustness and durability with cross-reactivity against different viral variants. Study: Differential antibody dynamics to SARS-CoV-2 infection …

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SARS-CoV-2 transmission model suggests primary school infection could be greater this autumn than in 2020

SARS-CoV-2 transmission model suggests primary school infection could be greater this autumn than in 2020

Credit: Unsplash/CC0 Public Domain The SARS-CoV-2 epidemic has already had a major impact on children’s education, with schools having been required to implement infection control measures that have led to long periods of absence and classroom closures. With the new school year underway, risk modeling specialists at the University of Bristol have developed a new …

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Why infection rates for COVID-19 among double-vaccinated older adults look worse than they are

Why infection rates for COVID-19 among double-vaccinated older adults look worse than they are

Choice of population data makes a big difference. Credit: Public Health England and NHS England, analysis by Colin Angus Recently, ITV journalist Robert Peston caught COVID, despite being double vaccinated. This set Peston wondering how common it is for the fully vaccinated to get the disease. His analysis is now complete. The headline is fairly …

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Memory killer T cells are primed in the spleen during influenza infection

Memory killer T cells are primed in the spleen during influenza infection

Scanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAID CD8+ T cells—known as “killer” T cells—are the assassins of the immune system. Once they are primed, they seek out and destroy other cells that are infected with virus or cells that …

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SARS-CoV-2-positive household members up infection risk for health care workers

SARS-CoV-2-positive household members up infection risk for health care workers

(HealthDay)—For vaccinated health care workers (HCWs), exposure to severe acute respiratory syndrome coronavirus (SARS-CoV-2)-positive household members is a risk factor associated with infection, according to a research letter published online Sept. 1 in JAMA Network Open. Yonatan Oster, M.D., from the Hebrew University of Jerusalem in Israel, and colleagues compared all vaccinated HCWs who had …

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