immune

Could future coronavirus variants fully dodge our immune system?

Could future coronavirus variants fully dodge our immune system?

Credit: Pixabay/CC0 Public Domain With every new variant of SARS-CoV-2 that emerges to cause a surge in cases, a worrisome question also arises: Could the virus eventually arrive at a set of mutations that would enable it to fully evade our immune response?  A new study, published in Nature, suggests that it will be hard for the …

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Discovery highlights the complex lifestyles of frontline immune cells

Discovery highlights the complex lifestyles of frontline immune cells

WEHI researcher Dr Michael Chopin have made a surprise discovery about how immune ‘sentinel’ cells are maintained, which could have implications for drugs in development for treating cancer. Credit: WEHI WEHI researchers have made a surprise discovery about how immune ‘sentinel’ cells are maintained, which could have implications for drugs in development for treating cancer. …

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Scientists examine kids’ unique immune systems as more fall victim to covid

Scientists examine kids’ unique immune systems as more fall victim to covid

Eighteen months into the covid-19 pandemic, with the delta variant fueling a massive resurgence of disease, many hospitals are hitting a heartbreaking new low. They’re now losing babies to the coronavirus. The first reported covid-related death of a newborn occurred in Orange County, Florida, and an infant has died in Mississippi. Merced County in California …

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Our immune system is as unique as a fingerprint or our DNA

Our immune system is as unique as a fingerprint or our DNA

A double stranded DNA fragment. Credit: Vcpmartin/Wikimedia/ CC BY-SA 4.0 Every person appears to have a completely unique immune system. Researchers from Utrecht University discovered this immune diversity after mapping antibodies from healthy and sick individuals. The discovery could help explain why, for example, corona vaccines appear to be less effective for some people. The …

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Moderna COVID-19 vaccine spurs lasting immune response: new study

Moderna COVID-19 vaccine spurs lasting immune response: new study

Transmission electron microscope image shows SARS-CoV-2, the virus that causes COVID-19, isolated from a patient in the U.S. Virus particles are shown emerging from the surface of cells cultured in the lab. The spikes on the outer edge of the virus particles give coronaviruses their name, crown-like. Credit: NIAID-RML A new study from La Jolla …

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Ebola vaccine regimen generates strong immune response in children and adults in a clinical trial in Sierra Leone

Ebola vaccine regimen generates strong immune response in children and adults in a clinical trial in Sierra Leone

Ebola virus. Credit: NIAID Johnson & Johnson’s two-dose Ebola vaccine regimen is safe, well tolerated and produces a strong immune response in people over the age of one, according to two new papers published in The Lancet Infectious Diseases. The EBOVAC-Salone study provides important further evidence for the potential of the regimen using the Ad26.ZEBOV …

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Study: SARS-CoV-2 triggers DNA damage response in Vero E6 cells. Image Credit: Festa/ Shutterstock

SARS-CoV-2 may have consequences to host cells beyond evoking an immune response

Recent data indicates that individuals are experiencing coronavirus disease 2019 (COVID-19) symptoms long after clearing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which suggests the virus has profound consequences to host cells. Study: SARS-CoV-2 triggers DNA damage response in Vero E6 cells. Image Credit: Festa/ Shutterstock RNA viruses, such as SAR-CoV-2, are renowned for …

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Off-target immune response could predict COVID-19 severity

Off-target immune response could predict COVID-19 severity

Credit: Pixabay/CC0 Public Domain The presence of special immune system defense molecules, called autoimmune antibodies, has been strongly tied to how poorly people fare when hospitalized with COVID-19, a new study shows. Led by researchers at NYU Grossman School of Medicine, the study detected the autoimmune antibodies in the blood of more than a third …

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Spread of Delta SARS-CoV-2 variant driven by combination of immune escape and increased infectivity

Spread of Delta SARS-CoV-2 variant driven by combination of immune escape and increased infectivity

Credit: Pixabay/CC0 Public Domain The Delta variant of SARS-CoV-2, which has become the dominant variant in countries including India and the UK, has most likely spread through its ability to evade neutralizing antibodies and its increased infectivity, say an international team of researchers. The findings are reported today in Nature. As SARS-CoV-2 replicates, errors in …

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cell

Metabolic changes in plasma and immune cells associated with COVID-19 severity, can predict patient survival

Credit: CC0 Public Domain COVID-19 patients have differing immune responses that lead to disease outcomes ranging from asymptomatic SARS-CoV-2 infection to death. After examining the blood samples from nearly 200 COVID-19 patients, researchers have uncovered underlying metabolic changes that regulate how immune cells react to the disease. These changes are associated with disease severity and …

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