immune

Study: SARS-CoV-2 BNT162b2 vaccine-induced humoral response and reactogenicity in individuals with prior COVID-19 disease. Image Credit: Irina Shatilova/Shutterstock

Study investigates whether immune responses to BNT162b2 vaccine differ in subjects with and without prior SARS-CoV-2 infection

The rollout of vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was expected to achieve population-level immunity preventing reinfection, and thus an eventual end to the pandemic of coronavirus disease 2019 (COVID-19). However, the emergence of variants that demonstrate resistance to neutralization by antibodies to the ancestral virus or earlier variants threatens …

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Study: Effect of cannabidiol on apoptosis and cellular interferon and interferon-stimulated gene responses to the SARS-CoV-2 genes ORF8, ORF10 and M protein. Image Credit: Dmytro Tyshchenko / Shutterstock

Cannabidiol may improve innate immune response against SARS-CoV-2

A recent study shows evidence that cannabidiol, an important active ingredient in the Cannabis sativa plant, can augment the antiviral innate immune response and prophylactically prime the innate antiviral response of cells – enabling in turn improved response against viruses such as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The research paper is currently …

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Study: A single-cell atlas reveals shared and distinct immune responses and metabolism during SARS-CoV-2 and HIV-1 infections. Image Credit: Design_Cells / Shutterstock

Similarities and dissimilarities in immune responses and metabolism in SARS-CoV-2 and HIV-1 infections

Among the various viral diseases, two of the most prevalent viruses that have affected millions of lives are severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and human immunodeficiency virus-1 (HIV-1). The current coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, has infected more than 319 million individuals and claimed more than 5.52 million lives worldwide. According to …

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Common cold coronaviruses hinder antibody immune response to SARS-CoV-2 infection

Common cold coronaviruses hinder antibody immune response to SARS-CoV-2 infection

Maureen McGargill, Ph.D., Department of Immunology, and graduate student Chun-Yang Lin. Credit: St. Jude Children’s Research Hospital Prior infection with coronaviruses that cause the common cold impedes the antibody immune response against SARS-CoV-2, the coronavirus responsible for COVID-19. The results from St. Jude Children’s Research Hospital appeared in print today in the journal Cell Host …

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Study finds evidence for increased activity of the brain’s immune system long before dementia onset

Study finds evidence for increased activity of the brain’s immune system long before dementia onset

Long before the onset of dementia, there is evidence for increased activity of the brain’s immune system. Researchers from DZNE and the University Hospital Bonn (UKB) come to this conclusion based on a study of more than 1,000 older adults. To this end, various proteins were measured in the cerebrospinal fluid: They served as so-called …

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Insight into immune cell communication may pave the way for new cancer vaccines

Insight into immune cell communication may pave the way for new cancer vaccines

In the past decade, immunotherapy has helped save the lives of many cancer patients, many with lung cancer, who might have otherwise faced almost certain death sentences. However, only about 20% of patients who received immune therapies -; designed to enhance or override natural limitations on immune system response -; saw sustained benefits from treatment. …

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Study: High seroconversion rate and SARS-CoV-2 Delta neutralization in PLWHIV vaccinated with BNT162b2. Image Credit: Naeblys/Shutterstock

Immune responses against SARS-CoV-2 Delta variant after BNT162b2 vaccination in people living with HIV

Most developed countries have enacted mass vaccination schemes to protect their population against coronavirus disease 2019 (COVID-19). However, as the vaccines were developed quickly, not much information is available on the safety or efficacy of these vaccines for those with diseases such as HIV. Study: High seroconversion rate and SARS-CoV-2 Delta neutralization …

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Study: Third COVID-19 Vaccine Dose Boosts Neutralising Antibodies in Poor Responders. Image Credit: davide bonaldo/Shutterstock

Does a COVID-19 vaccine booster improve the immune response of a poor responder?

Scientists have reported that the immune response elicited via coronavirus disease 2019 (COVID-19) vaccination or natural infection wanes off over time. The rapid outbreak of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) resulted in the COVID-19 pandemic that has claimed more than 5.27 million lives worldwide. Study: Third COVID-19 Vaccine Dose Boosts Neutralising …

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Can antiviral agents help immune systems fight mosquito-borne dengue?

Can antiviral agents help immune systems fight mosquito-borne dengue?

Aedes aegypti. Credit: UF/IFAS Photo Jim Newman Can the dengue virus be prevented using antiviral agents such as antibiotics or vaccines? Before considering that step, University of Florida scientists are taking a closer look at whether mosquito immune systems can be influenced enough to fight the virus as a control method. Ultimately, UF/IFAS scientists are …

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Study: Ad26.COV2.S or BNT162b2 Boosting of BNT162b2 Vaccinated Individuals. Image Credit: Tobias Arhelger/Shutterstock

Immune response of Pfizer vaccinees who received Moderna or Pfizer booster

The coronavirus disease 2019 (COVID-19) pandemic led to a spurt of activity to develop safe and effective vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first to be developed were the two messenger ribonucleic acid (mRNA) vaccines from Moderna and Pfizer, with 94% or higher efficacy reported from phase 3 clinical trials. …

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