Tag Archives: histone

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma 2

Elevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (TCGA) were split into two groups utilizing maximally selected rank statistic (Supplementary Figure 1A). Subjects with elevated HDAC2 expression experienced reduced …

Read More »