drug

Safety and efficacy data published for novel nusinersen drug delivery method for spinal muscular atrophy patients

Safety and efficacy data published for novel nusinersen drug delivery method for spinal muscular atrophy patients

Skeletal muscle fibers. Credit: Berkshire Community College Bioscience Image Library / Public domain A recently published paper details the safety and efficacy of nusinersen administration via a subcutaneous intrathecal catheter system (SIC) for SMA patients with advanced disease. SMA is a devastating genetic disease that leads to progressive degeneration of motor neurons that control movement, …

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Study: Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern. Image Credit: Susan Schmitz/ Shutterstock

Study finds FDA-approved drug has potent antiviral activity against SARS-CoV-2 and variants of concern

The coronavirus disease 2019 (COVID-19) pandemic has had overwhelming impacts on healthcare systems and has claimed over 4.9 million lives globally. The emerging novel variants of the severe acute respiratory syndrome coronavirus-2 (SARS‑CoV‑2) harbor vaccine escape capacities; besides, some individuals may still face vaccine access inequity. Hence, repurposing of clinically approved, safe, accessible, and active …

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Slow release of a drug, TT-10, improves heart attack recovery in a mouse model

Slow release of a drug, TT-10, improves heart attack recovery in a mouse model

Jianyi “Jay” Zhang. Credit: UAB A heart attack kills heart muscle cells, leading to a scar that weakens the heart, often leading to eventual heart failure. The lack of muscle repair is due to the very limited ability of mammalian heart muscle cells to proliferate, except for a brief period around birth. Thus, a pharmaceutical …

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Cystic fibrosis patients may see personalized treatments emerge from drug screening in a dish

Cystic fibrosis patients may see personalized treatments emerge from drug screening in a dish

New therapy screening assay showing functional rescue of lung progenitor cells from a person with Cystic Fibrosis caused by nonsense mutation (W1282X). Credit: Christine Bear, Hospital for Sick Kids and University of Toronto, Canada Stem cell researchers may soon have a new way to identify and develop novel, personalized therapies for patients with Cystic Fibrosis …

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A drug cocktail stops SARS-CoV-2 infection of stem cells

Credit: Kyoto University The COVID-19 vaccine is just one example of the rapid and global effort to stopping the pandemic. Drugs too are being developed. A new study by CiRA researchers shows that the combination of two drugs halts the infection of SARS-CoV-2, the virus responsible for COVID-19, in iPS cells. The influence of the …

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People hospitalized after taking veterinary drug for COVID

People hospitalized after taking veterinary drug for COVID

(HealthDay)—It’s a drug that’s been supported by some conservative media figures, but taking ivermectin to treat or prevent COVID-19 might land you in the hospital, a new study warns. Interest in the drug surged last summer as the highly contagious Delta variant took over the United States. But instead of protecting against the virus, the …

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Drug could help diabetic hearts recover after heart attack

Drug could help diabetic hearts recover after heart attack

Credit: Unsplash/CC0 Public Domain Researchers at the University of Oxford have identified a drug that could ultimately help improve heart function in people with diabetes who have heart attacks. The drug, currently in clinical trials as a potential treatment for a form of anemia, could help diabetic hearts to recover and reduce their risk of …

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Largest ever global study of tuberculosis identifies genetic causes of drug resistance

Largest ever global study of tuberculosis identifies genetic causes of drug resistance

Structural study of antibiotic opens the way for new TB treatments Credit: Shutterstock Using cutting-edge genomic sequencing techniques, researchers at the University of Oxford have identified almost all the genomic variation that gives people resistance to 13 of the most common tuberculosis (TB) drug treatments. The Comprehensive Resistance Prediction for Tuberculosis International Consortium (CRyPTIC) research …

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In quiet debut, Alzheimer's drug finds questions, skepticism

In quiet debut, Alzheimer’s drug finds questions, skepticism

This image provided by Biogen on Monday, June 7, 2021 shows a vial and packaging for the drug Aduhelm. The first new Alzheimer’s treatment in more than 20 years was hailed as a breakthrough when regulators approved it in June 2021, but its rollout has been slowed by questions about its price and how well …

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New drug targets vascular inflammation, drastically improving the long-term effectiveness of vascular procedures

New drug targets vascular inflammation, drastically improving the long-term effectiveness of vascular procedures

Blood vessel with an erythrocyte (red blood cell, E) within its lumen, endothelial cells forming its tunica intima (inner layer), and pericytes forming its tunica adventitia (outer layer) Credit: Robert M. Hunt/Wikipedia/CC BY 3.0 Cardiovascular procedures like bypass grafting and vessel stenting are some of the most common surgeries performed in the United States, but …

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