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Tag Archives: disease

Researchers discover new human autoinflammatory disease

Scientists from Australia and the US have discovered and identified the genetic cause of a previously unknown human autoinflammatory disease.The autoinflammatory disease, called CRIA syndrome, is caused by a mutation in a critical molecule in the cell death pathway, which leads to runaway inflammation and cell death. The discovery suggests …

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The right mouse model is crucial for Huntington’s disease drug development

A montage of three images of single striatal neurons transfected with a disease-associated version of huntingtin, the protein that causes Huntington’s disease. Nuclei of untransfected neurons are seen in the background (blue). The neuron in the center (yellow) contains an abnormal intracellular accumulation of huntingtin called an inclusion body (orange). …

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State legislators react to preventable disease outbreaks

(HealthDay)—Increases in vaccine-preventable disease (VPD) outbreaks are associated with an increase in proposed state legislation that would restrict vaccine exemptions, according to a research letter recently published in JAMA Pediatrics. Neal D. Goldstein, Ph.D., from Drexel University in Philadelphia, and colleagues linked state VPDs reported to the National Notifiable Diseases …

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Huntington’s Disease patients need better understanding of risks

Credit: CC0 Public Domain For patients with Huntington’s disease (HD), clinical trials can offer hope when there are no treatments available despite unknowns about whether the therapy will work or is safe. A new study in the Journal of Huntington’s Disease found that although the HD community appears highly optimistic …

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New insights into the effect of aging on cardiovascular disease

Credit: CC0 Public Domain Aging adults are more likely to have—and die from—cardiovascular disease than their younger counterparts. New basic science research finds reason to link biological aging to the development of narrowed, hardened arteries, independent of other risk factors like high cholesterol. Senior author Daniel Goldstein, M.D., of Michigan …

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