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Tag Archives: Cracking

Cracking the mystery of a rare bleeding disorder—and pursuing ‘off-the-shelf’ drugs to treat it

Credit: CC0 Public Domain Consider for a moment that your life is dominated by spontaneous nosebleeds, chronic stomach hemorrhaging, persistent anemia and a complex constellation of other manifestations, some potentially life-threatening. These symptoms characterize a rare genetic condition known as hereditary hemorrhagic telangiectasia, or HHT. The disorder disrupts the normal …

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Cracking ‘virus code’ could help fight cancer

Credit: CC0 Public Domain Virus experts from Cardiff University’s School of Medicine have uncovered, for the first time, how a virus known as Adenovirus type 26 (Ad26), which has been used effectively in a tamed form as a vaccine, can infect human cells. Ad26 is a virus of great interest …

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Cracking the code of a brain cancer that keeps coming back

Scientists looking for effective treatments against an aggressive form of medulloblastoma brain cancer, like the tumor shown in this MRI image of a child, report using a powerful new computer-assisted technology called single-cell transcriptomics to discover genetic drivers of the disease. When they blocked those molecular pathways it stopped the …

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