cells

Blocking an enzyme activity inside fat cells can reduce obesity in mice

Blocking an enzyme activity inside fat cells can reduce obesity in mice

Blocking the activity of an enzyme inside fat cells can decrease obesity and related health disorders in mice, according to new research led by the University of Michigan Life Sciences Institute. The study, published online Jan. 17 in the journal Nature Metabolism, focused on an enzyme called histone deacetylase 6 (or HDAC6) as an avenue …

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Researchers engineer enucleated cells to deliver therapeutics precisely to diseased tissues

Researchers engineer enucleated cells to deliver therapeutics precisely to diseased tissues

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health report successfully removing the nucleus out of a type of ubiquitous cell, known as enucleation, then using the genetically engineered cell as a unique cargo-carrier to deliver therapeutics precisely to diseased tissues. The findings published in …

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Study: When stem cells meet COVID-19: recent advances, challenges and future perspectives. Image Credit: Giovanni Cancemi/Shutterstock

Exploring the relationship between stem cells and COVID-19

Since December 2019, Wuhan, China, has been conducting influenza and related disease monitoring, and a number of cases of viral pneumonia have been discovered, all of which have been diagnosed as viral pneumonia or pulmonary infection. The World Health Organization (WHO) designated it a novel coronavirus (2019-nCoV) on January 12, 2020. The coronavirus Research Group dubbed …

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Study: Naïve T cells may be key to the low mortality of children with COVID-19. Image Credit: Martin Lauge Villadsen/Shutterstock

Naïve T cells suggested as critical to low mortality of children with COVID-19

During the ongoing coronavirus disease 2019 (COVID-19) pandemic, a peculiar phenomenon has been observed: younger individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had fewer cases and a lower mortality rate. It’s widely assumed that the human immune system develops continuously from birth to adolescence, and that immunity to infections is strongest in …

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cell

Nuclei-free cells prove utility in delivering therapeutics to diseased tissues

Credit: CC0 Public Domain Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health report successfully removing the nucleus out of a type of ubiquitous cell, known as enucleation, then using the genetically engineered cell as a unique cargo-carrier to deliver therapeutics precisely to diseased tissues. …

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CBD might help prime cells against COVID

CBD might help prime cells against COVID

Ball-and-stick model of the cannabidiol molecule. Credit: Public Domain Synthetic cannabidiol, a non-psychoactive compound also found in the cannabis plant, appears to prime the innate immune system of cells, potentially offering protection against pathogens such as SARS-CoV-2. Researchers found that synthetic cannabidiol (CBD) augments the anti-viral response of cells to three key proteins produced by …

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UCLA-led researchers improve method that was designed to kill HIV-infected cells

UCLA-led researchers improve method that was designed to kill HIV-infected cells

In a study using mice, a UCLA-led team of researchers have improved upon a method they developed in 2017 that was designed to kill HIV-infected cells. The advance could move scientists a step closer to being able to reduce the amount of virus, or even eliminate it, from infected people who are dependent on lifesaving …

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Machine learning illuminates genetic links between blood cells and disease

Machine learning illuminates genetic links between blood cells and disease

Credit: CC0 Public Domain Scientists from the Cambridge Baker Systems Genomics Initiative have used machine learning to create genetic predictors of blood cell traits, such as white blood cell counts, that are linked to chronic disease. The research, published today in the journal Cell Genomics, identified shared genetic architecture between blood cell traits and various …

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Research shows hemp compounds prevent coronavirus from entering human cells

Research shows hemp compounds prevent coronavirus from entering human cells

Credit: Oregon State University Hemp compounds identified by Oregon State University research via a chemical screening technique invented at OSU show the ability to prevent the virus that causes COVID-19 from entering human cells. Findings of the study led by Richard van Breemen, a researcher with Oregon State’s Global Hemp Innovation Center, College of Pharmacy …

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T cells from common colds cross-protect against infection with SARS-CoV-2

T cells from common colds cross-protect against infection with SARS-CoV-2

A colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAID A new study, published in Nature Communications and led by Imperial College London researchers, provides the first evidence of a protective role for these T cells. While previous studies have shown that T cells induced by other coronaviruses can recognize SARS-CoV-2, the new study …

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