Tag Archives: cancer

The ‘Goldilocks’ principle for curing brain cancer

The 'Goldilocks' principle for curing brain cancer 1

Cancer cell during cell division. Credit: National Institutes of Health In the story of Goldilocks, a little girl tastes three different bowls of porridge to find which is not too hot, not too cold, but just the right temperature. In a study published in Advanced Therapeutics, University of Minnesota Medical …

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    Factors predict low BMD in pediatric blood cancer survivors

    Factors predict low BMD in pediatric blood cancer survivors 2

    Low bone mineral density (BMD) is common in childhood leukemia and lymphoma survivors, according to a study published online Sept. 19 in Cancer. Hadley M. Bloomhardt, M.D., from the Yale School of Medicine in New Haven, Connecticut, and colleagues estimated the frequency of reduced BMD detected by off-therapy surveillance with …

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      PTSD symptoms tied to higher risk for ovarian cancer

      PTSD symptoms tied to higher risk for ovarian cancer 3

      (HealthDay)—Posttraumatic stress disorder (PTSD) symptoms are associated with an increased risk for ovarian cancer, especially among premenopausal women, according to a study published online Sept. 5 in Cancer Research. Andrea L. Roberts, M.P.H., Ph.D., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues used data from …

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        One-two punch knocks cancer cells out

        One-two punch knocks cancer cells out 5

        Credit: CC0 Public Domain A classic boxing move, the “one-two punch,” could also be effective against cancer: a left jab knocks cancer cells senseless, quickly followed by a right hook that knocks them out altogether. Researchers at the Netherlands Cancer Institute have shown that cancer cells are vulnerable to this …

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          Mutant cells team up to make an even deadlier blood cancer

          Mutant cells team up to make an even deadlier blood cancer 6

          In AML, defective blood cells (stained purple) are present. When the cells have a double mutation of both the IDH2 and SRSF2 genes (bottom right), the number of defective cells rises considerably, indicating a more lethal disease. Credit: Krainer lab/CSHL, 2019 Sometimes the whole is greater than the sum of …

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            A new route to blocking children’s bone cancer

            A new route to blocking children's bone cancer 9

            The lungs of an untreated mouse with Ewing sarcoma (left) contain numerous tumor cells (shown by luminescent colors) that have spread from the bone; the lungs of a mouse treated with a drug reducing the synthesis of glucocorticoids are almost free from the disease (right). Credit: Weizmann Instititue Ewing sarcoma …

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              How microbes hack into cells and why cancer drugs might block them

              How microbes hack into cells and why cancer drugs might block them 10

              Credit: A. KITTERMAN, Science Signaling {2019) DOI: 10.1126/scisignal.aau9894 No matter the pathogen—virus, bacterium or fungus—many “pick a specific type of lock” on the surface of cells, which allows the microbe to break and enter into the inner sanctum of the host’s genome. In a sweeping analysis on how microbes hack …

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