Deletion of the TPR gene led to lower levels of TPR and its associated protein HSF1 (left; lower panel) whereas rapamycin treatment reduced the tumor cells (dark blue cells) in the brains of mice (right, lower panel) Credit: Kanazawa University Ependymoma is a rare form of brain cancer that implicates …
Read More »Despite failures, chemo still promising against dangerous childhood brain cancer, DIPG
Adam Green, MD, and colleagues show that chemotherapy reaches DIPG tissue with enough concentration to be effective. Credit: University of Colorado Cancer Center The pediatric brain cancer known as diffuse intrinsic pontine glioma (DIPG) is almost uniformly fatal. In part, this is due to where and how it grows, forming …
Read More »How personalization and machine learning can improve cancer outreach ROI
Credit: CC0 Public Domain Researchers from Texas A&M, Iowa State University, Rice, and University of Texas Southwestern Medical Center published a new paper in the Journal of Marketing, which examines the efficacy of patient marketing. The study, forthcoming in the May issue of the Journal of Marketing, is titled “Improving …
Read More »Researchers develop new tool for performing cancer liquid biopsies
NYUAD Assistant Professor of Mechanical and Biomedical engineering Mohammad A. Qasaimeh and the first author of the study and the Research Scientist of Engineering at NYUAD, Muhammedin Deliorman Credit: NYU Abu Dhabi Cancer is one of the leading causes of death worldwide, and has been found to have a significantly …
Read More »3-D genetic structure in blood cancer important beyond DNA code changes
Credit: CC0 Public Domain Children with aggressive blood cancers have differences—not just in the DNA code of their blood cells—but also in the heavily twisted protein superstructure that controls access to genes. Led by researchers at NYU Grossman School of Medicine, a new study showed that whether T cell acute …
Read More »Study reveals an inherited origin of prostate cancer in families
Micrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia Vanderbilt researchers have identified haplotypes, ancestral fragments of DNA, that are associated with hereditary prostate cancer (HPC) in a first-of-its-kind genomic study made possible by the study of prostate cancer patients with family histories of the …
Read More »Interactions between cancer cells and fibroblasts promote metastasis
Credit: CC0 Public Domain In order to colonize other organs and grow into metastases, tumor cells that detach from the parent tumor need to manipulate their new microenvironment and create a ‘metastatic niche.’ Scientists from the German Cancer Research Center and the Heidelberg Institute for Stem Cell Technology and Experimental …
Read More »Stem cells and nerves interact in tissue regeneration and cancer progression
Cancer cells (green) are innervated with nerve cells (red). The cell nuclei (blue) are also visible. Credit: Institute of Oral Biology, University of Zurich Stem cells can generate a variety of specific tissues and are increasingly used for clinical applications such as the replacement of bone or cartilage. However, stem …
Read More »Study uncovers increasing global rates of liver cancer
Credit: CC0 Public Domain New research reveals rising rates of liver cancer around the world, despite advances aimed at preventing the disease. The findings are published early online in Cancer, a peer-reviewed journal of the American Cancer Society (ACS). To obtain trends and estimates of liver cancer by age, sex, …
Read More »Prostate cancer study finds molecular imaging could transform management of patients with aggressive cancer
Micrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia Results from a randomised controlled trial involving 300 prostate cancer patients find that a molecular imaging technique is more accurate than conventional medical imaging and recommends the scans be introduced into routine clinical practice. A medical …
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