Tag Archives: cancer

Micrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumour beyond the lymph node. Credit: Nephron/Wikipedia Diverse diseases like breast cancer can present challenges for clinicians, specifically on a cellular level. While one patient’s tumor may differ from another’s, the cells within the tumor of …

Credit: Tel Aviv University The connective tissue cells known as fibroblasts are vitally important for our recovery from injury. Sensing tissue damage, they gravitate to the site of a wound, instigating an inflammatory response that mends damaged tissue. A new Tel Aviv University study published in Nature Communications on September …

In a developing kidney, a mutant reader protein ENL gives rise to tumor-like structures. Credit: Laboratory of Chromatin Biology and Epigenetics at The Rockefeller University As an embryo develops, its cells must learn what to do with the thousands of genes they’ve been equipped with. That’s why each cell comes …

Mohammad Athar. Credit: UAB In laboratory experiments, a metabolic inhibitor was able to kill a variety of human cancer cells of the skin, breast, lung, cervix and soft tissues through a non-apoptotic route—catastrophic macropinocytosis. In mouse xenograft studies, the inhibitor acted synergistically with a common chemotherapy drug, cyclophosphamide, to reduce …

The World Health Organization has approved a biosimilar version of Trastuzumab—the drug used to treat breast cancer—that is generally 65 percent cheaper than the original The World Health Organization (WHO) announced Wednesday that it had for the first time approved a “biosimilar” medicine—one derived from living sources rather than chemicals—to …

Credit: CC0 Public Domain The progression of cancer has been studied extensively, and the key steps in this journey have been well mapped, at least in some solid tumors: Lesions to genes that confer risk of cancer accumulate and alter normal cell behaviors, giving rise, scientists believe, to early stage …

Credit: CC0 Public Domain African-Americans are at higher risk for cancer-associated venous thromboembolism (VTE) as compared with patients from other races. VTE is a condition in which a blood clot forms in a vein and then dislodges to travel in the bloodstream. In the U.S., VTE is responsible for an …

UC San Diego School of Medicine researchers developed a mathematical equation to predict when healthy liver cells become cancerous before tumors are visible in a standard clinical setting. Credit: UC San Diego Health Sciences By combining RNA sequencing, bioinformatics and mathematical modeling, University of California San Diego School of Medicine …

Credit: CC0 Public Domain Survival rates for patients with breast cancer have improved significantly in the last four decades, and many patients will eventually die from non-cancer-related causes. Researchers recently conducted the largest population-based long-term retrospective analysis of non-cancer causes of death among patients with breast cancer. The findings are …

Credit: CC0 Public Domain Endometrial cancer is the most common gynecological malignancy in the U.S. and the fourth most common cancer among women. In addition, endometrial cancer incidence rates are on the rise in the western world, suggesting that alterations in environmental factors such as diet, lifestyle, and the vaginal …