Targeted ultrasound for noninvasive diagnosis of brain cancer Targeted ultrasound for noninvasive diagnosis of brain cancer Credit: Unsplash/CC0 Public Domain Brain tumors are typically diagnosed using MRI imaging, as taking a sample for a tissue biopsy is risky and may not be possible due to tumor location or a patient’s …
Read More »Organoids help bridge gap between laboratory study and animal modeling of colorectal cancer
Organoids help bridge gap between laboratory study and animal modeling of colorectal cancer Organoids help bridge gap between laboratory study and animal modeling of colorectal cancer Credit: Unsplash/CC0 Public Domain Scientists at the Wake Forest Institute for Regenerative Medicine (WFIRM) have biofabricated human colorectal cancer miniature organs, called organoids, to …
Read More »Scientists discover novel drug target for pancreatic cancer
Scientists discover novel drug target for pancreatic cancer Scientists discover novel drug target for pancreatic cancer Axial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domain Scientists at Sanford Burnham Prebys Medical Discovery Institute have uncovered a novel drug target, a protein called PPP1R1B, that …
Read More »Scientists discover that a normal DNA repair process can become a major source of mutations in cancer
Scientists discover that a normal DNA repair process can become a major source of mutations in cancer Scientists discover that a normal DNA repair process can become a major source of mutations in cancer Credit: CC0 Public Domain Hypermutation is an unusual occurence that can lead to many nearby mutations …
Read More »Large international study pinpoints impact of TP53 gene mutations on blood cancer severity
Large international study pinpoints impact of TP53 gene mutations on blood cancer severity Large international study pinpoints impact of TP53 gene mutations on blood cancer severity Credit: Pixabay/CC0 Public Domain Considered the “guardian of the genome,” TP53 is the most commonly mutated gene in cancer. TP53‘s normal function is to …
Read More »Four-stranded DNA structures found to play role in breast cancer
Four-stranded DNA structures found to play role in breast cancer Four-stranded DNA structures found to play role in breast cancer From left to right, the structures of A-, B- and Z-DNA. Credit: Wikipedia Four stranded DNA structures—known as G-quadruplexes—have been shown to play a role in certain types of breast …
Read More »New blood cancer treatment options with chimeric antigen receptor-T cell therapy
New blood cancer treatment options with chimeric antigen receptor-T cell therapy New blood cancer treatment options with chimeric antigen receptor-T cell therapy Credit: CC0 Public Domain Dear Mayo Clinic: My brother was diagnosed with non-Hodgkin lymphoma a few years ago and has had several recurrences. I was reading about something …
Read More »Hearing loss linked to neurocognitive deficits in childhood cancer survivors
Hearing loss linked to neurocognitive deficits in childhood cancer survivors Hearing loss linked to neurocognitive deficits in childhood cancer survivors Research shows that severe hearing loss in childhood cancer survivors is associated with neurocognitive deficits independent of type of therapy. Credit: St. Jude Children’s Research Hospital Scientists at St. Jude …
Read More »Biologist uses genome database to investigate cancer cells
Biologist uses genome database to investigate cancer cells Biologist uses genome database to investigate cancer cells Florida State University researchers are contributing to the the Encyclopedia of DNA Elements, a project to better understand how the human genome works. Credit: National Institutes of Health. Florida State University Professor of Biological …
Read More »New drug targets for lethal brain cancer discovered
New drug targets for lethal brain cancer discovered New drug targets for lethal brain cancer discovered Glioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0 More than 200 genes with novel and known roles in glioblastoma—the most aggressive type of brain cancer—offer promising new drug targets. Researchers from the Wellcome Sanger Institute, …
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