cancer

Immunotherapy combination may benefit patients with non-small cell lung cancer resistant to single immunotherapy

Immunotherapy combination may benefit patients with non-small cell lung cancer resistant to single immunotherapy

Lung CA seen on CXR. Credit: James Heilman, MD/Wikipedia A combination of two drugs that open the floodgates to an immune system attack on cancer curtailed tumor growth in some patients with non-small cell lung cancer (NSCLC) that was resistant to a single immunotherapy agent, results from a recent clinical trial show. The addition of …

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Scientists find potential diagnostic and therapeutic target for lung cancer

Scientists find potential diagnostic and therapeutic target for lung cancer

Proposed model for the LCDR/hnRNP K/LAPTM5 axis promoting the pathogenesis of lung cancer. Credit: Gao Shan Chinese scientists recently reported the key role in tumor survival played by a histone-acetylation-regulated long noncoding RNA called lysosome cell death regulator (LCDR), providing a potential diagnostic and therapeutic target for lung cancer. Led by Prof. Gao Shan from …

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Improved ultrasound techniques for cancer diagnostics

Improved ultrasound techniques for cancer diagnostics

Credit: Pixabay/CC0 Public Domain To diagnose cancer a range of imaging techniques are used, such as MRI, CT and ET scans. However, ultrasound has the advantages of being a real-time, portable, widely available and cost-effective alternative. TU/e-researcher Anastasiia Panfilova investigated two promising ultrasound techniques, and developed an ultrasound contrast agent that can act as a …

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Study shows AI systems can accurately identify and grade prostate cancer

Study shows AI systems can accurately identify and grade prostate cancer

Researchers at Karolinska Institutet in Sweden have together with international collaborators completed a comprehensive international validation of artificial intelligence (AI) for diagnosing and grading prostate cancer. The study, published in Nature Medicine, shows that AI systems can identify and grade prostate cancer in tissue samples from different countries equally well as pathologists. The results suggest …

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Prostate cancer molecular feature with prognostic value, distinguishes ancestral differences

Prostate cancer molecular feature with prognostic value, distinguishes ancestral differences

Tissue microarray slides stained with the ERV3 antibody. A tumor tissue sample from a patient of BA ancestry is shown on the left while a sample from a patient of WA ancestry is shown on the right. A scatter plot of ERV3-1 percent positivity in tissue microarrays (TMA) from 52 BA and 90 WA patient …

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In cancer treatment, quality of life matters more and more

In cancer treatment, quality of life matters more and more

Credit: CC0 Public Domain Google “chemotherapy side effects” and the results abound. Nausea, anemia, infection, fertility problems, kidney problems, mouth sores. The list goes on and on. The seemingly inevitable downside of treating one’s cancer always seems to be a reduction in their quality of life. But a new Northwestern Medicine study found that a …

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New insights into molecular mechanisms that underpin the body's natural defenses against skin cancer

New insights into molecular mechanisms that underpin the body’s natural defenses against skin cancer

A study published today in Cell Reports reveals important insights into the molecular mechanisms that underpin the body’s natural defenses against the development of skin cancer. The findings offer new clues into the behavior of skin cancer at the cellular level, paving the way for potential new therapeutic targets to treat the disease. “We found …

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Blood test helps predict who may benefit from lung cancer screening

Blood test helps predict who may benefit from lung cancer screening

Credit: CC0 Public Domain A blood test, combined with a risk model based on an individual’s history, more accurately determines who is likely to benefit from lung cancer screening than the current U.S. recommendation, according to a study published today in the Journal of Clinical Oncology led by researchers from The University of Texas MD …

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Barrett esophagus, esophageal cancer diagnoses down during pandemic

Barrett esophagus, esophageal cancer diagnoses down during pandemic

(HealthDay)—New diagnoses of Barrett esophagus (BE) and esophageal cancer decreased during COVID-19, along with endoscopic ablation therapy, according to a report published online Nov. 18 in Gastroenterology. Arvind J. Trindade, M.D., from the Long Island Jewish Medical Center in New Hyde Park, New York, and colleagues evaluated claims data from the Premier Healthcare Database to …

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Describing a new mechanism that cancer cells use to invade

Describing a new mechanism that cancer cells use to invade

In this image a green transformed cell (right) is seen migrating. The magenta labels all outermost skin cells in this zebrafish embryo. Credit: King’s College London Transparent zebrafish skin was used to explore how pre-cancerous cells behave, enhancing our understanding of how cancers progress. The study, conducted by the Rosenblatt Lab and today published by …

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