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Tag Archives: attack

How diarrhea pathogens switch into attack mode at body temperature

Using special thermometers, bacteria detect whether they are in a warm-blooded host or not. Credit: RUB, Kramer Many bacterial pathogens excrete toxins as soon as they have entered the host in order to suppress its immune response. Researchers at Ruhr-Universität Bochum (RUB) have analyzed what happens on the molecular level …

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An out-of-the-box attack on diabetes

Inflammatory agents deplete growth differentiation factor 15 (GDF15) and kill susceptible beta cells to cause type 1 diabetes. Adding back GDF15 protects beta cells in treated mice. Credit: Rose Perry/PNNL A protein newly identified as important in type 1 diabetes can delay onset of the disease in diabetic mice, providing …

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New radiotracer offers opportunities for earlier intervention after heart attack

Binding specificity test. (A) PET/CT axial views, autoradiographs, and corresponding H&E stainings of 10-micron cross-sections prepared from MI nonblocked, blocked, and sham-operated rats. Autoradiographs and H&E stainings from nonblocked hearts show increased Ga-68-FAPI-04 uptake in infarcted area at 7 days after MI, whereas uptake is negligible after sham operation or …

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Heart attack discovery could give hope to people not able to be treated

2-photon microscopy image showing “straightening of heart attack scars” Credit: Robert D Hume Heart disease remains the largest killer in Australia and around the world. A new study has shown that a protein therapy- recombinant human platelet-derived growth factor-AB (rhPDGF-AB) – could improve outcomes following heart attack. After a heart …

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How do MAIT cells identify and attack foreign invaders?

Credit: CC0 Public Domain Melbourne researchers have identified what makes a specialised immune cell, known as mucosal-associated invariant T (MAIT), cells boost their numbers and attack foreign invaders at the site of the infection. T cells are a core component of the immune system, which recognise the presence of infectious …

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