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Do heart medications affect COVID-19 outcomes?

coronavirus , COVID-19
This transmission electron microscope image shows SARS-CoV-2 — also known as 2019-nCoV, the virus that causes COVID-19 — isolated from a patient in the US. Virus particles are shown emerging from the surface of cells cultured in the lab. The spikes on the outer edge of the virus particles give coronaviruses their name, crown-like. Credit: NIAID-RML

Cardiovascular drugs do not affect COVID-19 outcomes—such as disease severity, hospitalizations, or deaths—according to an analysis of all relevant studies published as of November 2020. The findings are published in the British Journal of Clinical Pharmacology.

Investigators included 429 studies in a qualitative analysis and 390 in a quantitative analysis.

The results indicate that patients at risk of or with confirmed COVID-19 should continue taking cardiovascular drugs as prescribed.

“This is the most comprehensive analysis of the extensive amount of data published in this area,” said senior author Munir Pirmohamed, MBChB, Ph.D., of the University of Liverpool, in the UK. “Given that we are still in the midst of a pandemic, the evidence base will continue to build, and we will therefore update our analysis.”

Analysis of 58 studies finds male sex and obesity are not associated with COVID-19 ICU mortality, but many factors are

More information:
Innocent G. Asiimwe et al, Cardiovascular drugs and COVID‐19 clinical outcomes: a living systematic review and meta‐analysis, British Journal of Clinical Pharmacology (2021). DOI: 10.1111/bcp.14927

Do heart medications affect COVID-19 outcomes? (2021, July 6)
retrieved 6 July 2021
from https://medicalxpress.com/news/2021-07-heart-medications-affect-covid-outcomes.html

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