Diseases

Diseases

COVID-19 dual-antibody therapies effective against variants in animal study

COVID-19 dual-antibody therapies effective against variants in animal study

MD/PhD student Rita Chen (left) and Brett Case, a postdoctoral researcher, prepare to work with SARS-CoV-2, the virus that causes COVID-19, under strict biosafety conditions. Chen, Case and MD/PhD student Emma Winkler co-led a study with virologist and immunologist Michael S. Diamond, MD, PhD, at the School of Medicine, to assess how well antibody-based drugs …

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COVID-19 outpatient thrombosis prevention trial ends early

COVID-19 outpatient thrombosis prevention trial ends early

Credit: CC0 Public Domain A year ago, investigators set out to study whether symptomatic COVID-19 outpatients should be given anticoagulant or antiplatelet therapy to prevent clots that were reported among some patients with COVID-19. The data collected to date, through a randomized, double-blinded, placebo-controlled trial sponsored by the National Heart, Lung, and Blood Institute (NHLBI), …

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SARS-CoV-2 infections may trigger antibody responses against multiple virus proteins

SARS-CoV-2 infections may trigger antibody responses against multiple virus proteins

Credit: Pixabay/CC0 Public Domain All coronaviruses produce four primary structural proteins and multiple nonstructural proteins. However, the majority of antibody-based SARS-CoV-2 research has focused on the spike and nucleocapsid proteins. A study published in PLOS Biology by Anna Heffron, Irene Ong and colleagues at the University of Wisconsin-Madison, U.S., suggests that immune responses may develop …

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US hitting encouraging milestones on virus deaths and shots

US hitting encouraging milestones on virus deaths and shots

In this June 17, 2021, file photo, an Orange County resident receives the COVID-19 vaccine at the Florida Division of Emergency Management mobile vaccination site at Camping World Stadium in Orlando, Fla. COVID-19 deaths in the U.S. have dipped below 300 a day for the first time since the early days of the disaster in …

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Canada's first case of Brazilian virus strain detected

India hits daily COVID vaccination record as free shots opened to all adults

Credit: CC0 Public Domain India recorded its highest-ever daily vaccination count on Monday as it opened up free shots to all adults. The progress with inoculations came on International Yoga Day, with Prime Minister Narendra Modi hailing the practice’s “protective” properties against the coronavirus. The country’s vaccination drive had significantly slowed in recent months due …

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Popular sepsis prediction tool less accurate than claimed

Popular sepsis prediction tool less accurate than claimed

Credit: CC0 Public Domain One in three patients who dies in a hospital has sepsis, a severe inflammatory response to an infection, marked by organ dysfunction, according to the Centers for Disease Control and Prevention. This heavy toll makes predicting which patients are at risk for developing the devastating condition a top priority for clinicians. …

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New analysis reveals link between birthdays and COVID-19 spread during the height of the pandemic

Credit: CC0 Public Domain In counties with already high COVID-19 infection rates, birthday bashes may have fueled infection spread during the peak months of the pandemic, according to a new analysis led by researchers at Harvard Medical School and the RAND Corporation. The report, published June 21 in JAMA Internal Medicine, shows that in counties …

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Specialists create software to study the spatial distribution of COVID-19

Specialists create software to study the spatial distribution of COVID-19

Figure 1. Connectivity Structure From Functional Networks Analysis Specialists from several centers, including the University of Valencia, have developed customized software that makes it possible to study the spatial distribution of the COVID-19 pandemic online. The tool works by tracking patients in space and time and thus facilitates controlling the transmission of the virus and …

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Clinical trial populations are often not proportionate to populations affected by the disease

Clinical trial populations are often not proportionate to populations affected by the disease

Credit: CC0 Public Domain U.S. researchers—who only a half century ago largely excluded women from clinical trials—now ensure they comprise half the study participants in National Institutes of Health-funded research. But inclusion doesn’t ensure women and men are properly represented in disease trials. Clinical trial sample populations should be proportionate to the population affected by …

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Free COVID vaccines for all Indian adults as Modi hails yoga 'shield'

Free COVID vaccines for all Indian adults as Modi hails yoga ‘shield’

Credit: Pixabay/CC0 Public Domain India opened up free vaccinations to all adults in an attempt to bolster its inoculation drive on Monday, as Prime Minister Narendra Modi kicked off a muted International Yoga Day hailing the practice’s “protective” properties against the virus. The country’s vaccination drive has significantly slowed in recent months due to a …

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